M. Lütgehetmann: search on Z-Library

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1

Chronic Hepatitis E in Rheumatology and Internal Medicine Patients: A Retrospective Multicenter European Cohort Study

Pischke, Sven, Peron, Jean-Marie, von Wulffen, Moritz, von Felden, Johann, Höner zu Siederdissen, Christoph, Fournier, Sophie, Lütgehetmann, Marc, Iking-Konert, Christoph, Bettinger, Dominik, Par, Gab

Journal:

Year:

2019

Language:

english

File:

PDF, 393 KB

english, 2019

2

Clinical evaluation of multiplex RT-PCR assays for the detection of influenza A/B and respiratory syncytial virus using a high throughput system

Eigner, Ulrich, Reucher, Svenja, Hefner, Nadine, Staffa-Peichl, Sandrine, Kolb, Melissa, Betz, Ulrike, Holfelder, Martin, Spier, Gene, Pfefferle, Susanne, Lütgehetmann, Marc

Journal:

Journal of Virological Methods

Year:

2019

Language:

english

File:

PDF, 420 KB

english, 2019

3

DAMIAN: an open source bioinformatics tool for fast, systematic and cohort based analysis of microorganisms in diagnostic samples

Alawi, Malik, Burkhardt, Lia, Indenbirken, Daniela, Reumann, Kerstin, Christopeit, Maximilian, Kröger, Nicolaus, Lütgehetmann, Marc, Aepfelbacher, Martin, Fischer, Nicole, Grundhoff, Adam

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 3.15 MB

english, 2019

4

Primary rat hepatocyte culture on 3D nanofibrous polymer scaffolds for toxicology and pharmaceutical research

Jeanette Bierwolf, Marc Lutgehetmann, Kai Feng, Johannes Erbes, Steffen Deichmann, Eva Toronyi, Christina Stieglitz, Bjoern Nashan, Peter X. Ma, Joerg M. Pollok

Journal:

Biotechnology and Bioengineering

Year:

2011

Language:

english

File:

PDF, 1.45 MB

english, 2011

5

Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B

Karsten Wursthorn, Marc Lutgehetmann, Maura Dandri, Tassilo Volz, Peter Buggisch, Bernhard Zollner, Thomas Longerich, Peter Schirmacher, Frauke Metzler, Myrga Zankel, Conrad Fischer, Graeme Currie, Ca

Journal:

Year:

2006

Language:

english

File:

PDF, 493 KB

english, 2006

6

Virion half-life in chronic hepatitis B infection is strongly correlated with levels of viremia

Maura Dandri, John M. Murray, Marc Lutgehetmann, Tassilo Volz, Ansgar W. Lohse, Joerg Petersen

Journal:

Year:

2008

Language:

english

File:

PDF, 366 KB

english, 2008

7

In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice

Marc Lutgehetmann, Tassilo Volz, Anne Köpke, Tim Broja, Eike Tigges, Ansgar W. Lohse, Eberhard Fuchs, John M. Murray, Joerg Petersen, Maura Dandri

Journal:

Year:

2010

Language:

english

File:

PDF, 486 KB

english, 2010

8

Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation

Marc Lütgehetmann, Lida V. Mancke, Tassilo Volz, Martina Helbig, Lena Allweiss, Till Bornscheuer, Joerg M. Pollok, Ansgar W. Lohse, J. Petersen, Stephan Urban, Maura Dandri

Journal:

Year:

2012

Language:

english

File:

PDF, 1.39 MB

english, 2012

9

Primary human hepatocytes on biodegradable poly(l-lactic acid) matrices: A promising model for improving transplantation efficiency with tissue engineering

Eva Török, Marc Lutgehetmann, Jeanette Bierwolf, Stefan Melbeck, Jochen Düllmann, Bjoern Nashan, Peter X. Ma, Joerg M. Pollok

Journal:

Liver Transplantation

Year:

2011

Language:

english

File:

PDF, 1.06 MB

english, 2011

10

The liver stage of Plasmodium berghei inhibits host cell apoptosis

Claudia Van De Sand, Sebastian Horstmann, Anja Schmidt, Angelika Sturm, Stefanie Bolte, Andreas Krueger, Marc Lütgehetmann, Jörg-Matthias Pollok, Claude Libert, Volker T. Heussler

Journal:

Molecular Microbiology

Year:

2005

Language:

english

File:

PDF, 1.05 MB

english, 2005

11

Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein

Petersen, Joerg, Dandri, Maura, Mier, Walter, Lütgehetmann, Marc, Volz, Tassilo, von Weizsäcker, Fritz, Haberkorn, Uwe, Fischer, Lutz, Pollok, Joerg-Matthias, Erbes, Berit

Journal:

Nature Biotechnology

Year:

2008

Language:

english

File:

PDF, 525 KB

english, 2008

12

RGB marking facilitates multicolor clonal cell tracking

Weber, Kristoffer, Thomaschewski, Michael, Warlich, Michael, Volz, Tassilo, Cornils, Kerstin, Niebuhr, Birte, Täger, Maike, Lütgehetmann, Marc, Pollok, Jörg-Matthias, Stocking, Carol

Journal:

Nature Medicine

Year:

2011

Language:

english

File:

PDF, 1.54 MB

english, 2011

13

Posttraumatic Stress Disorder in patients with traumatic brain injury

Judith Glaesser, Frank Neuner, Ralph Lütgehetmann, Roger Schmidt, Thomas Elbert

Journal:

Year:

2004

Language:

english

File:

PDF, 497 KB

english, 2004

14

35 In vivo inhibition of HBV infection by acylated pres peptides in the urokinase-type plasminogen activator (UPA) mouse model

J. Petersen, M. Dandri, M. Lütgehetmann, T. Volz, W. Mier, U. Haberkorn, F. von Weizsäcker, P. Gripon, S. Urban

Journal:

Journal of Hepatology

Year:

2006

Language:

english

File:

PDF, 135 KB

english, 2006

15

366 Functional integration of primary human hepatocytes after transplantation into uPA mice

T. Volz, M. Lutgehetmann, J.M. Pollok, L. Fischer, A. Quaas, M. Dandri, J. Petersen

Journal:

Journal of Hepatology

Year:

2006

Language:

english

File:

PDF, 131 KB

english, 2006

16

508 48 Weeks of adefovir mono therapy following 48 weeks of combination therapy with peginterferon alpha-2b and adefovir leads to additional biochemical and virological improvement

M. Lutgehetmann, K. Wursthorn, P. Buggisch, B. Zollner, M. Zankel, C. Fischer, C.L. Brosgart, J. Petersen

Journal:

Journal of Hepatology

Year:

2006

Language:

english

File:

PDF, 129 KB

english, 2006

17

[62] REPLICATIVE BUT NOT TRANSCRIPTIONAL ACTIVITY OF HBV'cccDNA IS IMPAIRED IN HBeAg-NEGATIVE PATIENTS

T. Volz, P. Wachtler, M. Lutgehetmann, S. Cinar, J. Petersen, M. Dandri

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 155 KB

english, 2007

18

[61] LOWER VIRAL PRODUCTION IN HBeAg-NEGATIVE PATIENTS IS DUE TO BOTH REDUCED POOL SIZE AND ACTIVITY OF THE HBV cecDNA

P. Wachtler, T. Volz, M. Lutgehetmann, K. Wursthorn, J. Petersen, M. Dandri

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 284 KB

english, 2007

19

[132] NUMBER OF HUMAN CELL CLUSTERS AFTER 24 HOURS PREDICTS OUTCOME OF HUMAN LIVER CELL TRANSPLANTATION EFFICACY IN THE uPA MOUSE SYSTEM

M. Konig, T. Volz, M. Lutgehetmann, J.M. Pollok, L. Fischer, M. Dandri, J. Petersen

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 155 KB

english, 2007

20

77 VIRAL LOADS CORRELATE WITH MILD SUPPRESSION OF THE TOLL-LIKE RECEPTOR SIGNALING IN THE LIVER OF CHRONIC HEPATITIS B PATIENTS

J.-H. Bockmann, M. Lütgehetmann, T. Volz, A. Köpke, A.W. Lohse, J. Petersen, M. Dandri

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 49 KB

english, 2009

21

97 GROWTH OF HEPADNAVIRUS INFECTED HEPATOCYTES STRONGLY REDUCES VIRION PRODUCTIVITY AND CCCDNA LOADS IN UPA MICE

T. Volz, M. Lütgehetmann, T. Broja, A.W. Lohse, J. Petersen, M. Dandri

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 70 KB

english, 2009

22

367 CYTOKINE EXPRESSION PROFILES IN THE LIVER OF INDIVIDUALS CHRONICALLY INFECTED WITH HEPATITIS B VIRUS DO NOT CORRELATE WITH VIROLOGICAL PARAMETERS

M. Lütgehetmann, J.-H. Bockmann, T. Volz, A. Köpke, A.W. Lohse, J. Petersen, M. Dandri

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 52 KB

english, 2009

23

922 RESCUE THERAPY WITH COMBINATION OF ENTECAVIR AND TENOFOVIR IN PATIENTS WITH CHRONIC HBV, ADVANCED FIBROSIS AND MULTIPLE PREVIOUS TREATMENT FAILURES IS SAFE AND HIGHLY EFFICIENT

M. Lütgehetmann, J. Schollmeyer, T. Volz, A. Lohse, P. Buggisch, M. Sterneck, T. Meyer, C. Sarrazin, M. Dandri, J. Petersen

Journal:

Journal of Hepatology

Year:

2009

Language:

english

File:

PDF, 50 KB

english, 2009

24

109 HEPATITIS B VIRUS RESTRAINS ACTIVATION OF SPECIFIC INTERFERON RESPONSIVE GENES IN HUMAN HEPATOCYTES REPOPULATING THE LIVER OF UPA/SCID MICE

T. Bornscheuer, T. Volz, M. Lütgehetmann, A.W. Lohse, J.H. Bockmann, J. Petersen, M. Dandri

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 49 KB

english, 2010

25

610 STRONG IN VIVO ANTIVIRAL EFFICACY OF A NEW L-DEOXYCYTIDINE DERIVATE IN HEPATITIS B VIRUS INFECTED HUMAN HEPATOCYTES REPOPULATING THE LIVER OF UPA/SCID MICE

E. Matthes, T. Volz, M. Lütgehetmann, J. Petersen, M. Dandri

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 49 KB

english, 2010

26

87 HEPATITIS B VIRUS INFECTION INHIBITS INTERFERON INDUCED NUCLEAR STAT-1 TRANSLOCATION AND ACTIVATION OF GENES OF THE INNATE RESPONSE IN HUMAN HEPATOCYTES IN CHIMERIC UPA MICE

T. Bornscheuer, L. Allweiss, T. Volz, M. Lutgehetmann, J. Petersen, A.W. Lohse, M. Dandri

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 41 KB

english, 2011

27

73 ADMINISTRATION OF THE ENTRY INHIBITOR MYRCLUDEX-B AFTER ESTABLISHMENT OF HEPATITIS B VIRUS INFECTION PREVENTS VIRAL SPREADING AMONG HUMAN HEPATOCYTES IN UPA MICE

M. Ben M'Barek, T. Volz, M. Lutgehetmann, T. Bornscheuer, L. Allweiss, A.W. Lohse, A. Alexandrov, S. Urban, J. Petersen, M. Dandri

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 41 KB

english, 2011

28

105 BLOCK OF HEPATITIS DELTA INFECTION BY THE ENTRY INHIBITOR MYRCLUDEX B IN UPA MICE: ESTABLISHMENT OF AN EFFICIENT MOUSE MODEL FOR HUMAN HBV/HDV INFECTION

M. Lutgehetmann, L.V. Mancke, L. Allweiss, T. Volz, M. Helbig, A.W. Lohse, A. Alexandrov, J. Petersen, S. Urban, M. Dandri

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 39 KB

english, 2011

29

515 LENIWIRAL ‘GENE ONTOLOGY’ (LEGO) VECTORS ENABLE HIGHLY EFFICIENT EX VIVO TRANSDUCTION OF HEPATOCYTES SUITABLE FOR CELL TRANSPLANTATION

M. Warlich, K. Weber, M. Thomaschewski, M. Lütgehetmann, T. Volz, J.M. Pollok, S. Gersting, J. Borsch, R. Santer, K. Ullrich, A.W. Lohse, M. Dandri, B. Fehse, D. Benten

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 58 KB

english, 2011

30

744 TREATMENT OF MULTIRESISTANT HBV PATIENTS WITH ENTECAVIR PLUS TENOFOVIR. 2 YEARS SAFETY AND EFFICACY ANALYSIS. AN INTERNATIONAL MULTICENTER COHORT STUDY

J. Petersen, M. Lutgehetmann, M. Buti, H. Janssen, A. Brown, P. Lampertico, F. Zoulim, H. Wedemeyer, M. Sterneck, T. Berg, C. Sarrazin, V. Ratziu, P. Buggisch

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 123 KB

english, 2011

31

42 PEGYLATED-INTERFERON-ALPHA ALONE OR IN COMBINATION WITH ENTECAVIR RESTORES ISG RESPONSIVENESS AND REDUCES INTRAHEPATIC VIRAL LOADS AND ANTIGENEMIA IN HEPATITIS B VIRUS INFECTED HUMANIZED MICE

L. Allweiss, M. Lütgehetmann, T. Volz, T. Bornscheuer, A.W. Lohse, J. Petersen, H. Ma, K. Klumpp, S. Fletcher, M. Dandri

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 75 KB

english, 2012

32

104 HEPATITIS D VIRUS CAN INFECT AND PERSIST IN HUMANIZED UPA/SCID MICE FOR AT LEAST SIX WEEKS BEFORE BEING RESCUED BY HEPATITIS B VIRUS SUPERINFECTION

M. Lutgehetmann, M. Helbig, K. Giersch, T. Volz, L. Allweiss, T. Bornscheuer, A.W. Lohse, J. Petersen, J. Taylor, M. Dandri

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 63 KB

english, 2012

33

456 PRETREATMENT OF HUMANIZED UPA/SCID MICE WITH INTERFERON ALPHA STRONGLY INHIBITS THE ESTABLISHMENT OF HEPATITIS B VIRUS INFECTION

T. Volz, J.-L. Braunschmidt, T. Bornscheuer, L. Allweiss, A.W. Lohse, J. Petersen, M. Lütgehetmann, M. Dandri

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 88 KB

english, 2012

34

Animal models for the study of HBV replication and its variants

M. Dandri, T.K. Volz, M. Lütgehetmann, J. Petersen

Journal:

Journal of Clinical Virology

Year:

2005

Language:

english

File:

PDF, 1.42 MB

english, 2005

35

O.184 In vivo inhibition of HBV infection by acylated preS peptides in the urokinase-type plasminogen activator (UPA) mouse model

J. Petersen, M. Dandri, M. Lütgehetmann, T. Volz, W. Mier, B. Lange, S. Urban

Journal:

Journal of Clinical Virology

Year:

2006

Language:

english

File:

PDF, 278 KB

english, 2006

36

P.122 Interim analysis: 48 weeks of combination therapy with peginterferon alpha-2b and adefovir followed by 48 weeks of adefovir monotherapy leads to additional biochemical and virological improvement

M. Lutgehetmann, K. Wursthon, M. Dandri, T. Volz, P. Buggisch, B. Zollner, M. Zankel, C. Fischer, M. Brosgart, J. Petersen

Journal:

Journal of Clinical Virology

Year:

2006

Language:

english

File:

PDF, 144 KB

english, 2006

37

Desperately Seeking Diarrhoea: Outbreak of Haemolytic Uraemic Syndrome Caused by Emerging Sorbitol-Fermenting Shiga Toxin-Producing Escherichia coli O157:H-, Germany, 2009

S. Nielsen, C. Frank, A. Fruth, A. Spode, R. Prager, A. Graff, A. Plenge-Bönig, S. Loos, M. Lütgehetmann, M. J. Kemper, D. E. Müller-Wiefel, D. Werber

Journal:

Zoonoses and Public Health

Year:

2011

Language:

english

File:

PDF, 100 KB

english, 2011

38

Experimental models and therapeutic approaches for HBV

Maura Dandri, Marc Lütgehetmann, Jörg Petersen

Journal:

Seminars in Immunopathology

Year:

2013

Language:

english

File:

PDF, 276 KB

english, 2013

39

Impaired Intrahepatic Hepatitis B Virus Productivity Contributes to Low Viremia in Most HBeAg-Negative Patients

Tassilo Volz, Marc Lutgehetmann, Paul Wachtler, Anna Jacob, Alexander Quaas, John M. Murray, Maura Dandri, Joerg Petersen

Journal:

Gastroenterology

Year:

2007

Language:

english

File:

PDF, 570 KB

english, 2007

40

Hepatitis B Virus Limits Response of Human Hepatocytes to Interferon-α in Chimeric Mice

Marc Lütgehetmann, Till Bornscheuer, Tassilo Volz, Lena Allweiss, Jan–Hendrick Bockmann, Joerg M. Pollok, Ansgar W. Lohse, Joerg Petersen, Maura Dandri

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 2.80 MB

english, 2011

41

Primary Human Hepatocytes from Metabolic-Disordered Children Recreate Highly Differentiated Liver-Tissue-Like Spheroids on Alginate Scaffolds

Bierwolf, Jeanette, Lutgehetmann, Marc, Deichmann, Steffen, Erbes, Johannes, Volz, Tassilo, Dandri, Maura, Cohen, Smadar, Nashan, Bjoern, Pollok, Joerg-Matthias

Journal:

Tissue Engineering Part A

Year:

2012

Language:

english

File:

PDF, 424 KB

english, 2012

42

The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus

Volz, Tassilo, Allweiss, Lena, ḾBarek, Mounira Ben, Warlich, Michael, Lohse, Ansgar W., Pollok, Jörg M., Alexandrov, Alexander, Urban, Stephan, Petersen, Jörg, Lütgehetmann, Marc, Dandri, Maura

Journal:

Journal of Hepatology

Year:

2013

Language:

english

File:

PDF, 1.46 MB

english, 2013

43

Mouse models of hepatitis B and delta virus infection

Dandri, Maura, Lütgehetmann, Marc

Journal:

Journal of Immunological Methods

Year:

2014

Language:

english

File:

PDF, 678 KB

english, 2014

44

1130 SPREADING OF HEPATITIS B VIRUS INFECTION IN UPA MICE IS SENSED BY INNATE ANTIVIRAL DEFENSE MECHANISMS OF HUMAN HEPATOCYTES

Volz, T., Lutgehetmann, M., Allweiss, L., Bornscheuer, T., Lohse, A.W., Ma, H., Klumpp, K., Petersen, J., Lopatin, U., Fletcher, S., Dandri, M.

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 40 KB

english, 2011

45

Feedback

Volz, T., Lutgehetmann, M., Allweiss, L., Bornscheuer, T., Lohse, A.W., Ma, H., Klumpp, K., Petersen, J., Lopatin, U., Fletcher, S., Dandri, M.

Journal:

Year:

2012

Language:

english

File:

PDF, 423 KB

english, 2012

46

1020 SAFETY AND EFFICACY OF ENTECAVIR AND TENOFOVIR COMBINATION-THERAPY IN HEPATITIS B PATIENTS WITH PREVIOUS TREATMENT FAILURES. AN INTERNATIONAL MULTICENTER COHORT STUDY

Petersen, J., Lütgehetmann, M., Zoulim, F., Janssen, H., Sterneck, M., Brown, A., Berg, T., Buggisch, P., Lampertico, P., Buti, M., Wedemeyer, H., Ratziu, V., Sarrazin, C.

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 67 KB

english, 2010

47

P179 BINDING OF HEPATITIS B VIRUS TO ITS CELLULAR RECEPTOR ALTERS THE EXPRESSION PROFILE OF GENES OF THE BILE ACID METABOLISM

Oehler, N., Volz, T., Kah, J., Allweiss, L., Giersch, K., Petersen, J., Lohse, A.W., Urban, S., Lutgehetmann, M., Heeren, J., Dandri, M.

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 59 KB

english, 2014

48

P178 INTERFERON ALPHA AND LAMBDA INHIBIT HBV REPLICATION WITH DISTINCT EFFICACY AND KINETICS OF GENE REGULATION IN HUMANIZED MICE

Giersch, K., Allweisss, L., Volz, T., Lohse, A.W., Petersen, J., Lutgehetmann, M., Dandri, M.

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 63 KB

english, 2014

49

P875 FIRST CASE REPORT OF A PATIENT WITH FIBROSING CHOLESTATIC HEPATITIS C AFTER LIVER TRANSPLANTATION TREATED WITH SOFOSBUVIR AND SIMEPREVIR

Lang, M., Polywka, S., Kluwe, J., Fischer, L., Jordan, S., Lütgehetmann, M., Nashan, B., Lohse, A.W., Sterneck, M.

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 59 KB

english, 2014

50

P886 RELEVANCE OF CHRONIC HEPATITIS E IN LIVER TRANSPLANT RECIPIENTS: A REAL-LIFE-SETTING

Galante, A., Pischke, S., Lang, M., Lütgehetmann, M., Polywka, S., Nashan, B., Lohse, A.W., Sterneck, M.

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 123 KB

english, 2014

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